Hubungan Pemberian Syringe Pump Norepinephrine dengan Kadar Gula Darah Acak pada Pasien di Ruang ICU RSUD Mardi Waluyo Kota Blitar

Authors

DOI:

https://doi.org/10.26699/jnk.v6i3.ART.p283-291

Keywords:

Syringe Pump Norepinephrine, Dosis, Kadar Gula Darah Acak

Abstract

Ketidakwaspadaan terhadap kontrol gula pasien yang mendapatkan norepinephrine berakibat perpanjangan masa rawat inap dan perburukan kondisi.Tujuan penelitian adalah menganalisis hubungan pemberian syringe pump norepinephrine dengan kadar gula darah acak pada pasien di ruang ICU RSUD Mardi Waluyo Kota Blitar. Rancangan penelitian menggunakan korelasi dengan pendekatan cross sectional. Populasi dalam penelitian ini adalah semua pasien ICU RSUD Mardi waluyo Kota Blitar yang diberikan syringe pump norepinephrine pada 29 Oktober – 22 November 2018. Jumlah sampel penelitian sebanyak 30 orang dengan menggunakan tehnik pengambilan sampel accidental sampling. Analisa data menggunakan Spearman’s rho. Hasil penelitian menunjukan ada hubungan yang lemah antara pemberian syringe pump norepinephrine dengan kadar gula darah acak pada pasien di ruang ICU RSUD Mardi Waluyo Kota Blitar dengan p value = 0,034 dan rs = 0,389. Norepinephrine dapat meningkatkan tekanan darah pada pasien kritis yang mengalami hipotensi, akan tetapi berakibat meningkatkan kadar gula darah acak, sehingga diharapkan adanya pemantauan kadar gula darah acak pada pasien kritis serta adanya monitoring penggunaan cairan diluent normal saline 0,9% dan  dextrose 5% yang harus disesuaikan dengan kondisi dari pasien yang mendapatkan norepinephrine.

 

Unawareness of blood sugar control in patients receiving norepinephrine resulted in an extended period of hospitalization and worsening conditions. The aim of the study was to analyze the correlation of giving norepinephrine syringe pump and random blood sugar levels of patients in ICU Mardi Waluyo Hospital, Blitar City. The study used correlation design with cross sectional approach. The population in this study was all ICU patients of Mardi Waluyo Hospital Blitar City who were given the norepinephrine syringe pump on 29 October - 22 November 2018. The sample was 30 people taken by using accidental sampling technique. The data analysis used Spearman's. The results showed there was a weak correlation between the administration of norepinephrine syringe pump and random blood sugar levels of patients in the ICU room at Mardi Waluyo Hospital, Blitar City with p value = 0.034 and rs = 0.389. Norepinephrine could increase blood pressure in critical patients who had hypotension, but it resulted in the increase of random blood sugar levels. It is expected to monitor random blood sugar level of critical patients as well as monitoring the use of diluent normal saline 0.9% and dextrose 5% which should be adapted to the conditions of patients who get norepinephrine.

Author Biography

Sandi Alfa Wiga Arsa, STIKes Patria HUsada Blitar

URL :

1. Google Scholar : Sandi Alfa WIga Arsa

2. Institute          : STIKes Patria Husada Blitar

References

Azimi-Nezhad, M., Ghayour-Mobarhan, M., Parizadeh, M. R., Safarian, M., Esmaeili, H., Parizadeh, S. M. J., … Ferns, G. (2008). Prevalence of type 2 diabetes mellitus in Iran and its relationship with gender, urbanisation, education, marital status and occupation. Singapore Medical Journal, 49(7), 571–576.

Beetz, N., & Hein, L. (2009a). Adrenaline and Noradrenaline. In Cardiovascular Hormone Systems (pp. 233–250). Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA. https://doi.org/10.1002/9783527626236.ch10

Beetz, N., & Hein, L. (2009b). Adrenaline and Noradrenaline. Cardiovascular Hormone Systems, 233–250. https://doi.org/10.1002/9783527626236.ch10

Coggan, J. S., Keller, D., Calì, C., Lehväslaiho, H., Markram, H., Schürmann, F., & Magistretti, P. J. (2018). Norepinephrine stimulates glycogenolysis in astrocytes to fuel neurons with lactate. PLoS Computational Biology, 14(8). https://doi.org/10.1371/journal.pcbi.1006392

Cooksley, T., McAvoy, T., & Haji-Michael, P. (2012). Glucose control in critical care oncology. Journal of the Intensive Care Society, 13(4), 289–292. https://doi.org/10.1177/175114371201300405

Falciglia, M., Freyberg, R. W., Almenoff, P. L., D’Alessio, D. A., & Render, M. L. (2009). Hyperglycemia-related mortality in critically ill patients varies with admission diagnosis. Critical Care Medicine, 37(12), 3001–3009. https://doi.org/10.1097/CCM.0b013e3181b083f7

Fitriani, N., & Nilamsari, N. (2017). Faktor-Faktor Yang Berhubungan Dengan Tekanan Darah Pada Pekerja Shift Dan Pekerja Non-Shift Di Pt. X Gresik. Journal of Industrial Hygiene and Occupational Health, 2(1), 57. https://doi.org/10.21111/jihoh.v2i1.1273

Hafid, M. (2014). HUBUNGAN RIWAYAT HIPERTENSI DENGAN KEJADIAN STROKE DI RSUP Dr. WAHIDIN SUDIROHUSODO MAKASSAR 2012. Jurnal Kesehatan UIN Alauddin, 7(1).

Han, M. J., Park, K. H., Shin, J. ho, & Kim, S. H. (2016). Influence of daily fluid balance prior to continuous renal replacement therapy on outcomes in critically ill patients. Journal of Korean Medical Science, 31(8), 1337–1344. https://doi.org/10.3346/jkms.2016.31.8.1337

Harahap, H., Hardinsyah, H., Setiawan, B., & Effendi, I. (2008). Hubungan Indeks Massa Tubuh, Jenis Kelamin, Usia, Golongan Darah Dan Riwayat Keturunan Dengan Tekanan Darah Pada Pegawai Negeri Di Pekan Baru. Penelitian Gizi Dan Makanan, 31, 69–73. Retrieved from http://ejournal.litbang.depkes.go.id/index.php/pgm/article/view/1515

Hermans, G., & Van den Berghe, G. (2015). Clinical review: Intensive care unit acquired weakness. Critical Care, 19(1). https://doi.org/10.1186/s13054-015-0993-7

Komeliani. (2012). Obesitas Dan Stress Dengan Kejadian Hipertensi. KESMAS - Jurnal Kesehatan Masyarakat, 7(2), 117–121. https://doi.org/10.15294/kemas.v7i2.2806

Marangou, A. G., Alford, F. P., Ward, G., Liskaser, F., Aitken, P. M., Weber, K. M., … Best, J. D. (1988). Hormonal effects of norepinephrine on acute glucose disposal in humans: A minimal model analysis. Metabolism, 37(9), 885–891. https://doi.org/10.1016/0026-0495(88)90124-2

Massicotte-Azarniouch, D., Amin, S. O., Hesketh, C., & Clark, E. G. (2017). Renal replacement therapy: Timing of initiation and intradialytic hypotension. American Journal of Respiratory and Critical Care Medicine, 196(1), 102–104. https://doi.org/10.1164/rccm.201611-2375RR

Modell, H., Cliff, W., Michael, J., McFarland, J., Wenderoth, M. P., & Wright, A. (2015). A physiologist’s view of homeostasis. Advances in Physiology Education, 39(4), 259–266. https://doi.org/10.1152/advan.00107.2015

Nair, A., Naik, V., & Rayani, B. (2017). FAST HUGS BID: Modified mnemonic for surgical patient. Indian Journal of Critical Care Medicine, 21(10), 713–714. https://doi.org/10.4103/ijccm.IJCCM_289_17

Nurmawati, T. (2018). Efektifitas pendidikan kesehatan dengan metode ekspositori tentang meal planning terhadap pola makan pasien dm tipe 2. Jurnal Ners Dan Kebidanan (Journal of Ners and Midwifery), 5(3), 257–262. https://doi.org/10.26699/jnk.v5i3.art.p257-262

Rudi, A., & Kwureh, H. N. (2017). Faktor Risiko yang Mempengaruhi Kadar Gula Darah Puasa pada Pengguna Layanan Laboratorium. Wawasan Kesehatan, 3(2), 33–39.

Silversides, J. A., Pinto, R., Kuint, R., Wald, R., Hladunewich, M. A., Lapinsky, S. E., & Adhikari, N. K. (2014). Fluid balance, intradialytic hypotension, and outcomes in critically ill patients undergoing renal replacement therapy: a cohort study. Critical Care, 18(6), 624. https://doi.org/10.1186/s13054-014-0624-8

Siskawati Suparmin. (2010). Beda kadar glukosa darah pada pria perokok dan bukan perokok tembakau usia 20-60 tahun di Salemba tahun 2009-2010. Fakultas Kedokteran Universitas Indonesia Jakarta.

Sumardi, F. S., Nawawi, A. M., & Maskoen, T. T. (2015). Perbandingan Efek Pemberian Norepinefrin Bolus Intravena dengan Norepinefrin Infus Kontinu dalam Tatalaksana Hipotensi, Laju Nadi, dan Nilai APGAR pada Seksio Sesarea dengan Anestesi Spinal. Jurnal Anestesi Perioperatif, 3(1), 14–23. https://doi.org/10.15851/jap.v3n1.375

Winta, A. E., Setiyorini, E., & Wulandari, N. A. (2018). Hubungan Kadar Gula Darah dengan Tekanan Darah pada Lansia Penderita Diabetes Tipe 2 ( The Correlation Of Blood Glucose Level and Blood Pressure of Elderly With Type 2 Diabetes ). Jurnal Ners Dan Kebidanan, 5(2), 163–171. https://doi.org/10.26699/jnk.v5i2.ART.p163

Yasmine, G. (2016). Association of Glucose Variability in the First 72 Hours of ICU Care with ICU Mortality in Critically-III Patients. Jurnal Penyakit Dalam Indonesia, 3.

Downloads

Published

05-12-2019

How to Cite

Prasetya, Y. D., & Arsa, S. A. W. (2019). Hubungan Pemberian Syringe Pump Norepinephrine dengan Kadar Gula Darah Acak pada Pasien di Ruang ICU RSUD Mardi Waluyo Kota Blitar. Jurnal Ners Dan Kebidanan (Journal of Ners and Midwifery), 6(3), 283–291. https://doi.org/10.26699/jnk.v6i3.ART.p283-291

Issue

Section

Article